Lab Director

Avram J. Holmes
Center for Advanced Human Brain Imaging Research
Rutgers University
119 Staged Research Building
661 Hoes Lane West
Piscataway, NJ 08854

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Dr. Holmes is an Associate Professor of Psychiatry at Rutgers University, affiliated with the Brain Health Institute, the Center for Advanced Human Brain Imaging Research, and the Rutgers-Princeton Center for Computational Cognitive Neuropsychiatry. Trained in clinical psychology and systems neuroscience, he studies the fundamental organization of large-scale human brain networks, with a particular focus on higher-level cognition and the intersection of emotion and cognition in psychiatric illness.

Study Staff

Kaley Joss
Department of Psychiatry
Rutgers University
119 Staged Research Building
661 Hoes Lane West
Piscataway, NJ 08854

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Kaley completed her bachelor’s in economics at the University of Washington, where she studied network economics under Dr. Alan Griffiths. At the Holmes Lab her research interests include building network-based models to analyze and characterize the time-varying patterns of brain connectivity that underlie individual differences in behavior.

Post Doctoral Fellows

Carrisa Cocuzza
Department of Psychiatry
Rutgers University
119 Staged Research Building
661 Hoes Lane West
Piscataway, NJ 08854

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Carrisa Cocuzza earned her PhD in Neuroscience at Rutgers University (NJ, USA) in 2022 under the advisement of Dr. Michael W. Cole. Her dissertation examined the extent that brain-network-based mechanisms can explain local and distributed processes, including visual category selectivity and cognitive control. She is interested in building on this work to assess how network architectures and dynamics are altered across dimensional symptom profiles in patients diagnosed with psychotic and affective disorders. Carrisa plans to incorporate computational approaches from machine learning and network control theory, along with multivariate sources of biological and behavioral data, to build mechanistically-informed models of transdiagnostic neurocognitive deficits.

Loïc Labache

Loïc Labache
Department of Psychiatry
Rutgers University
119 Staged Research Building
661 Hoes Lane West
Piscataway, NJ 08854

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Loïc Labache earned his BSc in Cognitive Science from the University of Bordeaux (2014) and his MSc in Cognitive Engineering from the Institut National Polytechnique de Bordeaux (2017). Prior to joining Yale University, he got his PhD under the supervision of Dr. Nathalie Tzourio-Mazoyer at the French Alternative Energies and Atomic Energy Commission (2020). His dissertation research focused on the elaboration of brain network atlases underpinning lateralized cognitive functions, with a particular emphasis on the study of inter-individual variability of language. He is interested in the link between resting-state and task-induced brain activity, as well as anatomo-functional bases of lateralized brain networks. His work will focus on the nested organization of cerebral networks, their dynamics and characteristics.

Ashlea Segal
Department of Psychology
413 Sheffield Sterling Strathcona Hall
1 Prospect Street
New Haven, CT 06511

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Ashlea is a postdoctoral research fellow at the Wu-Tsai Institute working with Professors Avram Holmes (Psychology) and Nenad Sestan (Neuroscience). Ashlea completed her PhD in Psychology and Neuroscience at the Turner Institute of Brain and Mental Health at Monash University (2023) in Melbourne, Australia under the supervision of Professor Alex Fornito. Ashlea’s PhD focused on mapping brain differences in psychiatric disorders across multiple spatial scales. She is interested in understanding how brain organization serves as bridge between one’s genes and one’s cognitive and behavioral processes, with a particular focus on individual neural variability in the context of psychiatric disorders.

Amber Howell

Department of Psychiatry
Rutgers University
119 Staged Research Building
661 Hoes Lane West
Piscataway, NJ 08854

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Amber is a postdoctoral fellow co-mentored by Linden Parkes and Avram Holmes at CAHBIR. Amber completed her undergraduate studies at the University of Wisconsin-Madison. After obtaining her bachelor’s degree, she was a research assistant at UC-Davis and Stanford University. She then completed her graduate studies at Yale University, where her dissertation work focused on thalamocortical circuitry in human and non-human primates. Amber is interested in how dynamic brain interactions arise from the structural architecture of the brain and how they are shaped by subcortical circuitry, using empirical and computational tools to bridge scales of analysis and integrate findings across species. Furthermore, she is interested in how dynamic brain patterns vary across individuals and how they relate to flexible cognition and behavior in typically and atypically-developing individuals.<

Graduate Students

Lydia Qu

Lydia Qu
Department of Psychology
413 Sheffield Sterling Strathcona Hall
1 Prospect Street
New Haven, CT 06511

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Yueyue (Lydia) Qu is a Psychology PhD student in the Neuroscience area. She earned her BA in Cognitive Neuroscience and Mathematics from Washington University in St. Louis (2021), where she worked with Ryan Bogdan and Deanna Barch. Lydia is interested in integrating various levels of analyses such as genetic, brain structure and fMRI with the ultimate goal of elucidating biomarkers of symptom dimensions across and within affective and psychotic disorders. She is also interested in investigating how dynamic interactions among functional networks underpin specific cascades of symptom development.

Xihan Zhang

Xihan Zhang
Department of Psychology
413 Sheffield Sterling Strathcona Hall
1 Prospect Street
New Haven, CT 06511

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Xihan is a PhD student in the Neuroscience area of Psychology. She received BS at Ocean University of China, and finished her thesis in system biology with Dr. Xinguang Zhu at Chinese Academy of Sciences. She then received MS in Computational Biology at Harvard, where she found her passion in human brain and finished thesis in Konklab. Then she worked with Dr. Marc Berman at University of Chicago for two years before joining the Holmes Lab. Xihan’s current interest focuses on the molecular and cellular bases of brain dynamics, how the features of brain signals are mapped to behavior space, and how the mapping function changes across development trajectory. 

Collaborators & Friends

Justin Baker – McLean Hospital 

Randy Buckner – Harvard University

Danilo Bzdok – McGill University

Elvisha Dhamala – Feinstein Institutes for Medical Research

Dost Öngür – McLean Hospital

Linden Parkes – Rutgers University

Jordan Smoller – MGH

Thomas Yeo – National University of Singapore

Xi-Nian Zuo – Beijing Normal University

Brain Genomics Superstruct Project (Open data release)