Functional Architecture of the Human Brain
The human brain is a complex web of interdigitated networks. Substantial progress has been made delineating the structure and function of aspects of this intricate architecture through post-mortem dissections in humans and invasive tract tracing and lesion studies in animals… READ MORE…
Genetic and Brain Bases of Human Variation
Identical experiences can produce drastically different behavioral and emotional responses across time, space and person. While these responses arise in a seemingly effortless manner, the ease with which they are experienced masks the intricate neural circuitry supporting their expression and regulation… READ MORE…
Neurobiological Markers of Psychiatric Illness
The brain’s exquisite complexity allows for the staggering diversity of human behavior. However, the evolutionary forces that enabled complex cognitive functions have also pushed our capabilities to their limits, increasing vulnerability for psychiatric illness. Using our understanding of the genetic and brain bases of individual differences in behavior as a foundation, we are exploring links between disturbances in network organization and clinical presentation in patient populations. Recent work from our group focused on the manner in which functional connectivity and network coherence is altered…. READ MORE…